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A new study by University of Texas Cancer centre has shown that men who gain weight rapidly between the ages of 25 to 40 are twice as likely to have recurrence of prostate cancer after surgery as men without rapid rates of weight gain.
According to the study published in the recent issue of Clinical Cancer Research, patients who are obese at the age of 40, and at the time of diagnosis with prostate cancer, also have a higher risk of recurrence.
Patients who gained an average of three and a half pounds a year have a higher risk for having their prostate cancer recur. They are more likely to experience biochemical failure, which is when their PSA level rises and their failure is likely to come sooner after surgery than in men who did not gain weight rapidly, or who were not obese.
In a study of 526 patients, men who gained weight faster between age 25 and the time of diagnosis of their prostate cancer were at greater risk for recurrence of the disease than men who gained weight more slowly or who were not obese.
The men at greater risk gained an average of 1.5 kilogram per year, or about three and a half pounds per year. Thus, a man who weighed 150 pounds at age 25,but weighed over 200 pounds by age 40 would be at a higher risk for recurrence.
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